Medical weight loss,
made for
menopause.
Personalized, provider-led GLP-1 for women in perimenopause and menopause. Licensed clinician care, delivered to your door. Cancel anytime, no auto-billing.
Compounded GLP-1, personalized to where you are in menopause
No auto-billing · Cancel anytime · No insurance needed
Takes 90 seconds · 100% Private · Free
Weight loss after 35 isn't just about eating less.
Menopause weight gain rarely comes down to one thing. Food noise, changing hormones, and years of diets that backfired all pile up at once. It's incredibly common, and it usually shows up like this:
Always hungry, never full.
Breakfast is barely over and lunch is already on the mind. That constant chatter about what to eat next is food noise, and it only gets louder in menopause.
- Always planning the next meal
- A mental tug-of-war that never clocks out
The hormones changed the rules.
Perimenopause and menopause rewire how the body stores fat and reads hunger. The same body simply responds differently than it did a few years ago.
- What worked at 35 falls flat now
- Same effort, a body that won’t cooperate
Lose it, gain it back. Diets make it worse.
Keto, fasting, counting every calorie, the cycle ends the same way. Each round of losing and regaining makes the next attempt harder and the weight more stubborn.
- The same pounds lost and found, again and again
- Every restart tougher than the last
None of it is a willpower problem.
Food noise, shifting hormones, years of yo-yo dieting. These are biological, not personal failings. For many women, GLP-1 medications could help treat the source of the cravings, so real effort finally has a chance to stick.
- Biology, not a lack of discipline
- Provider-led care built for this stage of life
Medical weight loss treatment
matched to your stage and goals
Weight loss in menopause isn't one size fits all. Choose the path that fits your stage, your goals, and your life, then a licensed provider confirms what's right for you.
Semaglutide Plan
GLP-1 receptor agonist
Member results
Josie members lose an average of 10-12% of their body weight in their first 6 months
What to expect
- A widely used GLP-1 for steady, gradual weight loss
- Available as a weekly injection or an oral option
Why Semaglutide?
Semaglutide is one of the most widely used GLP-1 medications. It is a solid first step if you are new to GLP-1 therapy and want a proven, steady approach.
Tirzepatide Plan
Dual GIP + GLP-1 agonist
Member results
Josie members lose an average of 12-15% of their body weight in their first 6 months
What to expect
- Dual-action mechanism designed for stronger appetite control
- Often chosen by women who have plateaued on another GLP-1
Why Tirzepatide?
Tirzepatide works on two hormonal pathways (GIP and GLP-1) and is designed for stronger appetite control. Many women choose it when they want the most effective option or have stalled on another GLP-1.
Microdose Plan
GLP-1 · micro-titration
Member results
94% of Josie members who reach their goal switch to the Microdose Maintenance Plan
What to expect
- A gentle, lower dose to help hold your results
- The affordable way to maintain once the weight is off
Why Microdose?
Once you reach your goal, microdosing uses a smaller dose to help maintain your results without the full-dose price, from $189/mo.
Results are based on self-reported data from Josie members on personalized treatment plans, including compounded GLP-1 medications and provider consultations. Averages reflect approximately 1,000 members on tirzepatide and 500 members on semaglutide who reported their weight on their intake questionnaire and on subsequent refill forms. Individual results may vary, and weight loss is not guaranteed.
Your medication and dose are determined by a licensed provider after reviewing your intake, only if appropriate for you. Compounded medications are not FDA-approved. GLP-1 medications carry serious risks, including the risk of thyroid C-cell tumors and medullary thyroid carcinoma (MTC). See the full safety information at the bottom of this page.
Every reason not to start, answered.
We hear the same questions from every woman starting out. Here's what they wish they knew at the stage you're at now.
Q“Is this actually real medical care?”
Real clinicians. Real prescriptions.
- Licensed U.S. providers experienced in GLP-1 and menopause
- Your plan matched to your body, stage, and goal
- Dosing your provider adjusts as you progress
Q“What if something feels off?”
Your care team, anytime.
- Message your care team whenever you need
- Video visits with a licensed provider
- No waiting rooms, no paperwork
Q“What if I run out or shipping is slow?”
No gaps in your treatment.
- Ships from licensed U.S. pharmacies
- Refills arrive on a regular schedule
- Pause, adjust, or cancel anytime
Q“Am I on my own after I pay?”
Never. We’re with you.
- No auto-billing, refill only when you’re ready
- Ongoing guidance built for menopause
- Step down to microdose maintenance when it’s time
What's in the vial matters.
So does where it comes from.
You shouldn't have to guess what's in your medication or where it comes from. With Josie, you don't.
Every batch passes four independent tests before it ships to your home.
- Sourced from licensed U.S. pharmacies
- Clinician-reviewed prescriptions
- Pharmaceutical-grade ingredients only
- Batch-tested before shipping
Potency
PassedAccurate dose, every time.
Passed dose verification
Sterility
PassedFree from bacteria and contaminants.
Passed injectable safety standards
pH
PassedBalanced for comfortable injections.
Passed injection tolerability range
Endotoxins
PassedBelow injectable safety thresholds.
Passed USP safety limits
Take 90 seconds · 100% private · free
Compounding pharmacies are licensed and inspected by state Boards of Pharmacy. Compounded medications are not FDA-approved, and the FDA does not review them for safety, effectiveness, or quality before they are marketed.
Same medication.
Very different experience.
Personalized GLP-1 plans for your stage of menopause
Generic, fixed plans. You adapt to them.
Provider guidance built for women in midlife
One-size-fits-all, not menopause-aware.
Treatment matched to your body and goals
Same dose for everyone.
Dosing titrated by your provider to ease side effects
Side effects handled reactively, if at all.
Message your care team anytime
Hard to reach anyone after you pay.
100% online. Free, discreet shipping.
Pharmacy lines and long waits.
Women like you.
Real results.
Testimonials reflect individual experiences and are not a guarantee of results. Weight-loss results are self-reported, not typical, and vary based on starting weight, adherence, and individual health.
Hear it from women like you
Real members on what changed once they stopped fighting their hormones alone.
Videos reflect individual member experiences and are not a guarantee of results. Individual results vary.
How it works.
And how fast.
Answer a few questions. We'll handle the rest.
- No commitment required
- 100% online, takes under 2 minutes
- 100% private and secure
Takes 90 seconds · 100% private · free
What is your
goal weight?
A licensed clinician builds your plan, for your body.
- Dosing personalized to your stage of menopause
- Treatment matched to your body and goals
- Licensed, U.S.-based providers
Takes 90 seconds · 100% private · free
CertifiedEverything you need. Delivered to your door.
- Direct from licensed U.S. compounding pharmacies
- Free, discreet shipping
- Medication, care team access, and your personalized plan
Takes 90 seconds · 100% private · free
Your plan evolves as your body does.
- Monthly clinician check-in, adjustments as needed
- Simple refills, only when you're ready
- No auto-billing. Pause, adjust, or cancel anytime
- Unlimited messaging with your care team
Takes 90 seconds · 100% private · free
Lower dose. Same medication. Just micro.
A gentle, affordable dose to help hold your results once you've hit your goal.
Takes 90 seconds · 100% private · free
Your plan includes
Everything. All-in.
- Your personalized compounded GLP-1, prescribed by a licensed provider
- Free, discreet shipping straight to your door
- Unlimited care team access, message or video anytime
- Ongoing provider check-ins, with dose adjustments as you go
- No auto-billing. Pause, adjust, or cancel anytime
- Pharmacy lab-tested medication, with microdose maintenance when you reach your goal
Takes 90 seconds · 100% private · free
Your questions. Honest answers.
Everything you want to know before getting started. And once you begin, you have unlimited access to your care team for virtual visits or support, anytime.
What happens if I don't see results?
Your plan is built to adapt. If the scale isn't moving, your licensed provider can adjust your dose or switch your medication based on the progress you report on your refill forms and your check-ins. And because there's no auto-billing and you can cancel anytime, you're never locked into something that isn't working for you. Weight loss is never guaranteed, and individual results vary.
What is included when I start?
Everything you need to get going: a personalized compounded GLP-1 prescription if your provider approves you, free and discreet shipping to your door, unlimited messaging and video access to your care team, and ongoing provider check-ins that adjust your plan as your body changes.
What treatments do you offer?
Through Josie, licensed providers may prescribe compounded GLP-1 medications, including semaglutide and tirzepatide, available as a weekly injection or a dissolvable tablet. Once you reach your goal, a lower-dose microdose plan can help you maintain. Your provider decides what is appropriate for you after reviewing your intake.
How does it work?
Three steps. You answer a short online questionnaire about your health and goals. A licensed U.S. provider reviews it, usually within a day, and builds a plan if treatment is right for you. If approved, your medication ships discreetly to your door, and your care team stays with you for check-ins and adjustments.
What states do you serve?
Josie serves women in all 50 U.S. states. Care is delivered entirely online, so you can start from home wherever you live.
Do I need insurance?
No. Josie does not bill insurance, so there are no claims, prior authorizations, or surprise denials to deal with. You also do not need an existing prescription to get started.
What is your cancellation policy?
There is no auto-billing and no long-term lock-in. You refill only when you are ready, and you can pause or cancel anytime. If you have a question about an order, your care team can help.
I have a prescription from another weight-loss company. Can I continue at my current dose?
Possibly. Share your current medication and dose during your intake, and your Josie provider will review your history to decide whether you can continue at a similar dose or should adjust. Your safety drives that decision, not your previous plan.
Is this as legitimate as seeing a local clinician?
Yes. You are cared for by licensed U.S. providers who review your health history and write real prescriptions, the same standard of care you would expect in person. The difference is convenience: visits, messaging, and refills happen online, with no waiting rooms.
How quickly will I see results?
It varies from person to person and depends on your starting point, your dose, and consistency. Your provider will set realistic expectations and adjust your plan over time. Individual results are not typical or guaranteed.
I am nervous about injections. What should I expect?
That is common, and many women find it is easier than they feared. GLP-1 injections use a very small needle just under the skin, and your care team walks you through it. If injections still are not for you, ask your provider about a dissolvable tablet option.
Are compounded GLP-1 medications FDA-approved?
No. Compounded medications are not FDA-approved, and the FDA does not review them for safety, effectiveness, or quality before they are marketed. When prescribed, they are prepared by a licensed U.S. compounding pharmacy. Josie is not a compounding pharmacy.
We're here when
you need us.
Always available
Your care team, 24/7
Message or video, anytime
Reach your care team from your dashboard
Email us
team@joinjosie.com
Important Safety Information
Website content is for informational purposes only and is not medical advice. Always talk with a licensed medical provider about your care options.
Compounded GLP-1 medications are not FDA-approved. The FDA does not review compounded medications for safety, effectiveness, or quality before marketing. Compounded medications are not the same as FDA-approved generics. Josie is not a compounding pharmacy; if prescribed, compounded medications are prepared by a licensed compounding pharmacy.
Josie partners with U.S. licensed compounding pharmacies. Compounded medications are not FDA-approved, and the FDA does not review them for safety, effectiveness, or quality before they are marketed.
Compounded medications are prepared by licensed compounding pharmacies that are registered with and inspected by state Boards of Pharmacy. However, the FDA does not review compounded medications for safety, effectiveness, or quality before they are marketed.
GLP-1 medications are prescription drugs that should be taken only under the supervision of a licensed health care professional. GLP-1 medications carry serious risks, including the risk of thyroid C-cell tumors and medullary thyroid carcinoma (MTC). Tell your provider right away if you notice a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. Other possible side effects include nausea, vomiting, diarrhea, and pancreatitis. Do not use a GLP-1 medication if you or a family member has had MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Treatment is only available if a licensed provider determines it is appropriate for you after reviewing your intake. This page does not constitute medical advice and is not a guarantee of treatment or results. Individual results vary.
You may be redirected to a third-party platform that connects you with licensed providers and pharmacy services. Josie does not provide medical advice and does not control provider decisions. External services are governed by their own terms and privacy policies.